Pyrimidine nucleosides
Apexbio Technology LLC 2-Deoxycytidine,1g CAS# 951-77-9
2-Deoxycytidine is a cytidine analog [1]. 2-Deoxycytidine prevents DNA methylation by incorporating itself into newly synthesizing DNA strand. 2-Deoxycytidine also binds to DNA methyltransferase irreversibly and hinders its activity. Thus, 2-deoxycytidine was approved as the most efective demethylating agent for the treatment of cancer [1]. 2-Deoxycytidine at clinically achievable and nontoxic concentrations (≥ 100 μmol/L) protected normal bone marrow progenitor cells against the inhibitory effects of co-administered, high concentrations of 3’-azido-3’-deoxythymidine (AZT) (≥ 10 μmol/L). In normal bone marrow mononuclear cells (BMMC), 2-deoxycytidine also significantly corrected AZT-mediated depletion of intracellular thymidine triphosphate and 2-deoxycytidine triphosphate levels. Furthermore, 2-deoxycytidine reduced the intracellular accumulation of AZT triphosphate and its DNA incorporation in BMMC [2]. Other sizes are also available. Please inqury us for quote.
Medchemexpress LLC Deoxycytidine triphosphate disodium | 102783-51-7 | 99.0% | 511.12 | 25 MG
Deoxycytidine triphosphate (dCTP) disodium is a nucleoside triphosphate that contains the pyrimidine base cytosine. It is for research use only.
- Nucleoside triphosphate containing cytosine
- Suitable for research use
- Related to DNA/RNA synthesis
- Used in oligonucleotide and nucleotide analog research
Medchemexpress LLC Deoxycytidine triphosphate | 2056-98-6 | MFCD00135938 | 98.2% | 467.16 g/mol | C9H16N3O13P3 | 50 MG
Deoxycytidine triphosphate (dCTP) is a deoxynucleoside triphosphate used as a substrate for DNA polymerases in molecular biology. Supplied as a laboratory reagent, it is intended for enzymatic DNA synthesis applications such as PCR, cDNA synthesis, and DNA sequencing.
- High purity suitable for enzymatic DNA synthesis and PCR.
- Accurate molecular weight and formula for reagent planning.
- Supplied in a convenient small-scale package for method development.
- Stable when stored under recommended conditions to preserve activity.
- Commonly used as a deoxynucleotide substrate in sequencing and amplification workflows.
Medchemexpress LLC 3′-Deoxyuridine | 7057-27-4 | 98.0% | 228.20 | 1 ML
3′-Deoxyuridine is a potential anticancer and antiviral agent. It has been shown to inhibit bovine diarrhea virus (BVDV) production.
- Potential anticancer agent.
- Potential antiviral agent, inhibiting bovine diarrhea virus (BVDV) production.
Alkali Scientific 2' Deoxycytidine Hydrochloride, 25 G
2' Deoxycytidine Hydrochloride (25 g) is a high-purity nucleoside, used extensively in molecular biology for research into DNA synthesis, modification, and metabolism. Deoxycytidine is a key building block of DNA, and its hydrochloride form is ideal for biochemical and enzymatic assays, such as PCR and DNA sequencing. This reagent is particularly useful for studies related to nucleotide incorporation, DNA repair processes, and the role of deoxyribonucleosides in cellular functions. Deoxycytidine Hydrochloride is frequently used in molecular and genetic research laboratories to facilitate detailed studies of genetic expression and nucleotide behavior.
eMolecules 951-77-9 | ChemScene | 2-Deoxycytidine | 5g | 536774267 | CS-0010105 | MFCD23103479 | 227.22 | C9H13N3O4
ChemScene | 2-Deoxycytidine | 5g | 536774267 | CS-0010105 | 951-77-9 | MFCD23103479 | 227.220 | C9H13N3O4
Sigma Aldrich Fine Chemicals Biosciences 5-Bromo-2′-deoxyuridine | 59-14-3 | MFCD00006529 | 1g
5-Bromo-2′-deoxyuridine | Purity: 99% | Mol Wt: 307.1 | 59-14-3 | MFCD00006529 | 1g
Medchemexpress LLC 2'-Deoxycytidine-5'-monophosphoric acid | 1032-65-1 | 99.99% | 307.20 | 100 MG
2'-Deoxycytidine-5'-monophosphate (also known as 2'-Deoxycytidine-5'-monophosphoric acid) is an endogenous metabolite. It is a deoxynucleotide building block that constitutes DNA. It can serve as a substrate for UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, thus supporting DNA biosynthesis.
- Endogenous metabolite
- Deoxynucleotide building block of DNA
- Can be used as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, supporting DNA biosynthesis
Medchemexpress LLC 2'-Deoxycytidine | 951-77-9 | 99.9% | 50 G
2'-Deoxycytidine is a deoxyribonucleoside that can inhibit the biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and can be used for cancer research.
- Synonyms: Deoxycytidine, Cytosine deoxyriboside, Deoxyribose cytidine
- Molecular weight: 227.22
- Formula: C9H13N3O4
- Appearance: Solid
- Color: White to off-white
- Storage conditions: 4°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light).
Medchemexpress LLC Cytidine, 2'-deoxy-5-(hydroxymethyl) | 7226-77-9 | 100.0% | C10H15N3O5 | 10MG
5-Hydroxymethyl-2'-deoxycytidine (5hmdC) is a nucleoside analog used as a reference reagent in epigenetic and DNA modification research. It is commonly used to study DNA methylation and demethylation pathways and for analytical method development and quantification assays.
- Used as a reference standard for DNA methylation and demethylation studies.
- High purity confirmed by HPLC (99.96%).
- Available in solid and solution formats, including DMSO solutions for immediate use.
- Suitable for analytical method development and quantification assays.
- Supplied with a certificate of analysis providing batch-specific quality data.
Medchemexpress LLC HY-D0186 100mg Medchemexpress, 2'-Deoxyuridine CAS:951-78-0 Purity:>98%
Medchemexpress, HY-D0186 100mg 2'-Deoxyuridine CAS:951-78-0 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-112669 100mg Medchemexpress, 5-Chloro-2'-deoxyuridine 5-Chlorodeoxyuridine;CldU CAS:50-90-8 Purity:98%
Medchemexpress,HY-112669 100mg 5-Chloro-2'-deoxyuridine 5-Chlorodeoxyuridine;CldU CAS:50-90-8 Formula:C9H11ClN2O5 5-Chloro-2'-deoxyuridine, a thymine analog, is to study the potential of hypochlorous acid damage to DNA and DNA precursors. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.