Pyrimidine nucleosides
Cayman Chemical 5-Chloro-2-deoxyurIdIn 100mg
A thymidine analog that is readily incorporated, following phosphorylation, into newly synthesized DNA in place of thymidine; can be detected immunologically in cells and tissues
Medchemexpress LLC 2'-deoxycytidine-2'-13C | >98.0% | 228.21 g/mol | C8 13CH13N3O4 | 1 MG
13C-labeled 2'-deoxycytidine supplied as a research-grade stable isotope standard for analytical and tracer studies. Supplied in a small 1 mg pack with reported high purity, it is intended for use in metabolite tracing, mass spectrometry calibration, and other analytical applications.
- Stable isotope labeled (13C) standard for analytical methods.
- Suitable for metabolite tracing and mass spectrometry quantitation.
- High reported purity (>98.0%).
- Supplied in a small research pack suitable for analytical use.
- Provided as a solid, easy to store and handle in laboratory settings.
Sigma Aldrich Fine Chemicals Biosciences 2',3'-Dideoxycytidine >=98% (HPLC) | 7481-89-2 | MFCD00012188 | 100MG
2',3'-Dideoxycytidine >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 211.22 | 7481-89-2 | MFCD00012188 | 100MG
Research Products International Corp RPI 2'-Deoxycytidine Hydrochloride, 25 Grams
2'-Deoxycytidine Hydrochloride
Research Products International Corp 5-Bromo-2'-Deoxyuridine, 500 Milligrams
Thymidine analog used for study of DNA synthesis. This analog selectively incorporates into cellular DNA during S-phase. Supplied as white powder.
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 100.0% | 10 MM 1 ML
2'-Deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. It serves as a precursor in the synthesis of Edoxudine and is an analogue of 5-ethynyl-2'-deoxyuridine. Additionally, 2'-deoxyuridine reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury, showing promise for Alzheimer's disease (AD) research.
- Brain-penetrant pyrimidines nucleotide associated with nervous system diseases.
- Increases chromosome breakage.
- Decreases thymidylate synthetase activity.
- Reduces microglial activation.
- Improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury.
- Promising for Alzheimer's disease (AD) research.
Medchemexpress LLC Uridine, 2'-deoxy-4-thio- | 5580-20-1 | MFCD00058457 | 99.8% | 244.27 g·mol⁻¹ | C9H12N2O4S | 5 MG
4-Thio-2'-deoxyuridine is a sulfur-substituted deoxyuridine nucleoside analog supplied as a light-yellow solid and used as a research reagent in studies of DNA synthesis, nucleoside metabolism, and antitumor mechanisms. It is characterized for biochemical and cell-based experiments and provided with supporting analytical data.
- High purity (99.8%) for research applications.
- Sulfur-substituted nucleoside for incorporation and metabolism studies.
- Stable solid form with recommended low-temperature storage.
- Well-characterized molecular properties (C9H12N2O4S; 244.27 g·mol⁻¹).
- Available in small quantities suitable for laboratory-scale experiments.
Medchemexpress LLC 4-thio-2'-deoxyuridine | 5580-20-1 | MFCD00058457 | 99.8% | 244.27 g/mol | C9H12N2O4S | 100 MG
4-Thio-2'-deoxyuridine is a sulfur-substituted deoxyuridine nucleoside analogue used in biochemical and nucleic acid research, including studies of nucleic acid chemistry and incorporation into oligonucleotides. It has molecular formula C9H12N2O4S, molecular weight 244.27 g/mol, and a reported purity of 99.78%.
- Sulfur-substituted deoxyuridine analogue useful for nucleic acid studies.
- High reported purity (99.8%), suitable for analytical and synthetic applications.
- Available in multiple pack sizes for research-scale work.
- Provided with certificate of analysis and safety data sheet for quality and handling.
- Offered in solid form and as 10 mM DMSO solution for convenient use.
Medchemexpress LLC KTX-951 | 2573298-36-7 | 99.6% | 850.95 | 1 MG
KTX-951 is an orally active PROTAC degrader targeting IRAK4 and IMiD (Ikaros/Aiolos) substrates. It exhibits a Kd of 3.5 nM for IRAK4, with DC50 values of 13 nM, 14 nM, and 13 nM for IRAK4, Ikaros, and Aiolos, respectively. This compound also shows an IC50 of 35 nM for OCl-Ly10 CTG and demonstrates antitumor activity.
- Orally active PROTAC degrader
- Targets IRAK4 and IMiD (Ikaros/Aiolos) substrates
- Kd of 3.5 nM for IRAK4
- Molecular weight: 850.95
- Formula: C46H52F2N8O6
- Appearance: Solid, light yellow to yellow
- Purity: 99.60%
- Soluble in DMSO at 50 mg/mL (58.76 mM)
- Oral bioavailability in rats: 22% at 10 mg/kg
- Oral bioavailability in dogs: 57% at 10 mg/kg
Accela Chembio Inc THYMIDINE | 25G | 50-89-5 | MFCD00006537 | 98% | RETEST PERIOD: 1800DAYS | LIGHT SENSITIVE/+4c
THYMIDINE | 25G | 50-89-5 | MFCD00006537 | 98% | RETEST PERIOD: 1800DAYS | LIGHT SENSITIVE/+4c
Sigma Aldrich Fine Chemicals Biosciences 5-fluoro-2-deoxyuridine 5-5MG
5-fluoro-2-deoxyuridine 5-5MG
Medchemexpress LLC 2'-Deoxycytidine | 951-77-9 | MFCD00006547 | 99.95% | 25 G
2'-Deoxycytidine is a deoxyribonucleoside that can inhibit the biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and is utilized in cancer research.
- Inhibits biological effects of Bromodeoxyuridine (Brdu)
- Essential for nucleic acid synthesis
- Utilized in cancer research
- Acts as a human endogenous metabolite
- Functions as a microbial metabolite
- Demonstrated to inhibit tumor growth in vivo